Have a look at the [System.Data.SQLite Downloads](https://system.data.sqlite.org/index.html/doc/trunk/www/downloads.wiki) page... there (usually) is a dependency on the Microsoft Visual C++ Runtime Library. Installing Visual Studio will get these (as you found), but there are downloads from Microsoft of just the library, which you'd need to include in the MSI or deploy manually. There also appear to be (from skimming that page) "static" versions of the packages that don't have the dependency on the runtime libraries (but will, therefore, be bigger, I assume).