Greetings, I am using the latest release of SQLITE3 as of this writing ( Version 3.34.0 ). After inserting 60,000 records into the following table (for test purposes): CREATE TABLE PlayerConnections ( TargetPlayerId INTEGER NOT NULL, SourcePlayerId INTEGER NOT NULL ); When attempting to execute the following same exact query 60,000 times in a simple for() loop: "SELECT 1 FROM PlayerConnections WHERE (TargetPlayerId = 20000 AND SourcePlayerId = 1)" Executing this loop takes 60-80 seconds to perform such a simple query The interesting thing is that the first queries are executed quickly, as expected, 500-1000 queries take <1ms. By the time the loop reaches the 50000th iteration, approximately 1 in 3 queries cost 15ms to execute, sometimes 30ms, and sometimes 45ms resulting in a serious performance decrease over-all.