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Tips for getting SQLite under Python to perform better with more RAM?
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> Do you have a blog post on how you've managed this?

Mainly it's just "use Cloud Run" - to use it you need to package up your (stateless) web application in a Docker container which Cloud Run will then start running (and charging for) when requests come in and switch back off when the traffic stops.

I made some notes on how to use it here: https://til.simonwillison.net/cloudrun/ship-dockerfile-to-cloud-run

I usually deploy to it with my "datasette publish cloudrun" tool though, which is described here: https://docs.datasette.io/en/stable/publish.html#publishing-to-google-cloud-run