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Enabling JSON1 extension in the sqlite3.c amalgamation at compile time
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Your first step should be to test if the extension is really activated.
So run a test with only the preprocessor, something like:

gcc -E sqlite3.c -DSQLITE_ENABLE_JSON1 >sqlite3.txt

and check the output for the JSON1 functionality.
If the JSON1 functions are not recognised, are there any specific error messages or codes?